In this issue are highlights of ABNE's activities in 11 focus countries in Africa in building functional biosafety regulatory systems: Burkina Faso, Ghana, Kenya, Malawi, Mali, Mozambique, Nigeria, Tanzania, Togo, and Uganda. These countries were identified based on criteria such as technological readiness, political will, ongoing biotechnology research and development programmes, and ongoing process in receiving biosafety applications. ABNE realizes the continually changing flux of progress on biosafety regulatory affairs in individual countries. ABNE also notes and appreciates positive policy and regulatory developments in some countries in Africa.